Edwin Southern developed a blotting technique for DNA in 1973, thereby creating a staple of molecular biology laboratory procedures still used after several decades. It became a seminal technology for studying the structure of DNA. The story of the creation and dissemination of this technology, which was not patented and was freely distributed throughout the scientific community, stands as a case study in open science. The Southern blot was developed at a time when attitudes about commercial intrusion into health (...) research were beginning to change and the practical value of molecular genetics was becoming apparent to industry. Interest from industry in fundamental molecular biological techniques meant that scientists began to think about commercial uses of their work even in otherwise "basic" research. The unpatented Southern blot is contrasted with later patented technologies, particularly microarray methods, which were created in the same environment by many of the same people, but which followed significant changes to UK policies encouraging commercialization of academic research and a norm shift friendlier to such commercialization within academic molecular biology. Professor Southern's personal experience illuminates how the technologies evolved, and his views provide insight into how scientists' attitudes about commercialization have changed. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Minutes of the Annual General Meeting 2023Cornelis de Waal, Editor-in-Chief, Richard Kenneth Atkins, André De Tienne, Director and General Editor, and Elizabeth Cooke[as approved on January 17, 2024]The Annual General Meeting of the Charles S. Peirce Society was held in conjunction with the Eastern Division Meeting of the APA on January 5, 2023, at the Sheraton Le Centre, Montréal, Quebec. Rosa Maria Mayorga chaired the meeting and called it (...) to order at 12:38 p.m.1. Moment of SilenceThe annual meeting began with a moment of silence in memory of Peirce scholars who passed away in the last year.2. Approval of Minutes of the 2022 MeetingMinutes of the 2022 Annual General Meeting had been posted online. Copies were also distributed at the annual meeting. Rosa Maria Mayorga asked for a motion to approve the minutes. James Liszka so moved and Fabienne Forster seconded. The minutes were approved unanimously.3. Report from the Executive CommitteeRichard Kenneth Atkins submitted the following report.The Executive Committee Meeting was held virtually via email. All members of the Executive Committee were contacted and responded regarding the agenda and items.Agenda Items(A) Non-profit Status Update:On December 5, 2022, we received notification from the IRS that we have been legally approved as a public non-profit foundation.(B) Funding for Scholarship:Every year, we set aside a certain amount of funding for scholarship, usually 2/3rds of the year's income. This includes the $1,000 set aside for the Peirce Essay prize. Atkins reported that the income this past year was $6,597.06. 2/3rds of that is $4,400. Atkins requested that that amount of money be set aside for funding for scholarship, with which the committee unanimously agreed.(C) Next Year's AGM:Atkins proposed that we continue to hold our annual conference in conjunction with the E-APA in New York, NY, especially as this keeps us in line with the calendar year which is also our fiscal year as a nonprofit. The committee unanimously agreed. [End Page 118](D) Any Other Business:Cornelis de Waal suggested that we add to the agenda for the annual business meeting a moment of silence to commemorate Peirce scholars who passed this year. The Executive Committee unanimously agreed.4. Report from the Transactions of the Charles S. Peirce SocietyCornelis de Waal submitted the following report on behalf of the Transactions of the Charles S. Peirce Society. Richard Kenneth Atkins read the report on his behalf.During the 2022 calendar year we produced four issues of the Transactions. We encountered some problems with the first issue, because the printer suffered a ransomware attack. This apparently wreaked havoc with their system and caused significant delay in the completion of the issue.Likely due to the (after) effects of the pandemic, quality submissions to the journal were down significantly, both in the Peirce segment and in the non-Peirce segment of the journal. In addition, there was a significant drop in book reviews. The latter led to the resignation of our long-term book review editor, Henrik Rydenfelt. For the last two months I have been taking over for him, and I'm first-hand experiencing some of the challenges, even including publishers simply not following through on requests for books. We did, though, publish a book symposium on James Liszka's Charles Peirce on Ethics, Esthetics and the Normative Sciences, and we have another book symposium forthcoming on Chris Voparil's Reconstructing Pragmatism: Richard Rorty and the Classical Pragmatists. Besides a number of excellent papers on Peirce, we published some very nice papers in American philosophy. The latter include an extensive portrait of Edwin Bissell Holt, a discussion of the use of the term pragmatism in 18th century Germany, the first English translation of two texts by Wilhelm Jerusalem, as well as work on George Santayana, Jonathan Edwards, and Emily Dickinson.With Henrik gone, the editorial team is now down to Robert Lane and me (hopefully briefly returning to the traditional Robin-Hare setup). I'll be attending the upcoming SAAP meeting in Denver, and Bob is planning to attend as well... (shrink)

Explains the concept of deconstruction, discusses the influence of the philosopher Jacques Derrida, and looks at examples of deconstruction in art and architecture.